Lung Pathology in Antiphospholipid Syndrome

The lung in the antiphospholipid syndrome.

Patients with antiphospholipid syndrome (APS) may develop a broad spectrum of pulmonary disease. Pulmonary thromboembolism and pulmonary hypertension are the most common complications, but microvascular pulmonary thrombosis, pulmonary capillaritis, and alveolar haemorrhage have also been reported. Clinicians should seriously consider these types of vascular injury when evaluating patients with ...

The lung physician and the antiphospholipid syndrome.

Correspondence: G. Hillerdal, Karolinska Sjukhuset, 171 76 Stockholm, Sweden. The antiphospholipid syndrome (APS) is characterized by repeated thrombosis on both the arterial and the venous side, and a high titre of antiphospholipid antibodies. Thrombosis can affect any organ, cause myocardial infarction, hepatic infarction or Budd-Chiari syndrome, renal problems, adrenal crisis, cerebral infar...

Anticardiolipin syndrome: antiphospholipid syndrome.

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Antiphospholipid syndrome

APS can be primary or secondary. Primary antiphospholipid syndrome occurs in the absence of any other related disease. Secondary antiphospholipid syndrome is often associated with systemic lupus erythematosus and less frequently with infections, drugs and other diseases. Serologic markers are antiphospholipid antibodies, lupus anticoagulant and anticardiolipin. In rare cases, APS leads to rapid...

Antiphospholipid syndrome